SCHEMBL1787931

SCHEMBL1787931

CC(C)CC(COC(=O)c1ccccc1)(COC(=O)c1ccccc1)CC(C)C

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.71
HIF1A Q16665 1/20 0.71
TDP1 Q9NUW8 4/20 0.50
ALDH1A1 P00352 4/20 0.50
SLC6A3 Q01959 2/20 0.50
LMNA P02545 2/20 0.50
HTR1A P08908 1/20 0.50
CYP2D6 P10635 1/20 0.50
SCN1A P35498 1/20 0.50
SCN5A Q14524 1/20 0.50
SCN2A Q99250 1/20 0.50
SCN3A Q9NY46 1/20 0.50
ADRB2 P07550 2/20 0.48
ADRB1 P08588 2/20 0.48
ADRB3 P13945 2/20 0.48
TSHR P16473 4/20 0.47
KMT2A Q03164 3/20 0.47
SLC6A2 P23975 1/20 0.47
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9947108 0.92 MAPK1 (0.65) MAPK1HIF1ATDP1ALDH1A1SLC6A3
SCHEMBL9945704 0.92 MAPK1 (0.65) MAPK1HIF1ATDP1ALDH1A1SLC6A3
SCHEMBL16045158 0.91 MAPK1 (0.59) MAPK1HIF1ATDP1ALDH1A1SLC6A3
SCHEMBL15233919 0.90 MAPK1 (0.58) MAPK1HIF1ATDP1ALDH1A1SLC6A3
SCHEMBL20217140 0.88 MAPK1 (0.59) MAPK1HIF1ATDP1ALDH1A1SLC6A3
SCHEMBL16047661 0.87 MAPK1 (0.54) MAPK1HIF1ATDP1ALDH1A1SLC6A3
SCHEMBL16048199 0.87 MAPK1 (0.54) MAPK1HIF1ATDP1ALDH1A1SLC6A3
SCHEMBL12336443 0.86 MAPK1 (0.56) MAPK1HIF1ATDP1ALDH1A1SLC6A3
SCHEMBL18489548 0.84 MAPK1 (0.57) MAPK1HIF1ATDP1ALDH1A1SLC6A3
SCHEMBL27620 0.84 MAPK1 (1.00) MAPK1HIF1ATDP1ALDH1A1SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3135697-B1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2019-08-14 EP claimed
US-10208145-B2 Catalyst component for olefin polymerization, and catalyst containing the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-02-19 US claimed
EP-1472293-B1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2017-04-26 EP claimed
US-20170073441-A1 Catalyst Component For Olefin Polymerization, and Catalyst Containing the Same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2017-03-16 US claimed
EP-3135697-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST THEREOF China Petroleum & Chemical Corporation (CN) 2017-03-01 EP claimed
CN-105566742-A Preparation method of polyolefin alloy SINOPEC YANGZI PETROCHEMICAL 2016-05-11 CN claimed
CN-103571045-B The preparation method of anti-impact polypropylene in-reactor alloy SINOPEC CORP. (CN) 2016-04-20 CN claimed
CN-105482008-A Method for preparing polyolefin multi-phase copolymer SINOPEC YANGZI PETROCHEMICAL 2016-04-13 CN claimed
CN-105085746-A Catalyst component for propylene polymerization, and catalyst thereof CHINA PETROLEUM & CHEMICAL 2015-11-25 CN claimed
US-7388061-B2 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-06-17 US claimed
US-20050239636-A1 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-10-27 US claimed
US-20050096389-A1 Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof CHINA PETROLEUM & CHEMICAL (CN) 2005-05-05 US claimed
EP-3517555-B1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2024-11-27 EP disclosed
EP-3517553-B1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2023-11-08 EP disclosed
US-11325994-B2 Catalyst component for olefin polymerization, catalyst, and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2022-05-10 US disclosed
EP-3805277-A1 PROCATALYST COMPOSITIONS USEFUL FOR LOW COMONOMER INCORPORATION AND PROCESS FOR PREPARING THE SAME Dow Global Technologies LLC (US) 2021-04-14 EP disclosed
EP-1478617-A1 POLYOL ESTER COMPOUNDS USEFUL IN PREPARATION OF A CATALYST FOR OLEFINS POLYMERIZATION, PROCESS FOR PREPARING THE SAME AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2004-11-24 EP disclosed
EP-1472293-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2004-11-03 EP disclosed
WO-2003068828-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2003-08-21 WO disclosed
WO-2003068723-A1 POLYOL ESTER COMPOUNDS USEFUL IN PREPARATION OF A CATALYST FOR OLEFINS POLYMERIZATION, PROCESS FOR PREPARING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2003-08-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050096389-A1 Polyol ester compounds useful in preparation of a catalyst for olefins polymerization, process for preparing the same and use thereof CBR3, CBR1, OXER1 MAPK1 2038/4885HIF1A 2560/4885TDP1 4722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.