SCHEMBL17880386

SCHEMBL17880386

Brc1cc(-c2cccnc2)cc(-c2ccc3ccc4cccc5ccc2c3c45)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 11/20 0.47
CYP11B2 P19099 10/20 0.47
CYP19A1 P11511 5/20 0.43
CYP17A1 P05093 5/20 0.43
PGR P06401 1/20 0.40
CYP3A4 P08684 4/20 0.40
ALDH1A1 P00352 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2A6 P11509 2/20 0.40
KDM4E B2RXH2 2/20 0.39
LMNA P02545 1/20 0.39
HPGD P15428 1/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MEN1 O00255 1/20 0.38
PSIP1 O75475 1/20 0.38
AXL P30530 1/20 0.38
MKNK1 Q9BUB5 1/20 0.38
MKNK2 Q9HBH9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16484804 0.88 CYP11B1 (0.49) CYP11B1CYP11B2CYP19A1CYP17A1PGR
SCHEMBL16483029 0.87 CYP11B1 (0.51) CYP11B1CYP11B2CYP19A1CYP17A1PGR
SCHEMBL16483784 0.87 CYP11B1 (0.51) CYP11B1CYP11B2CYP19A1CYP17A1PGR
SCHEMBL19785700 0.85 CYP11B1 (0.50) CYP11B1CYP11B2CYP19A1CYP17A1CYP3A4
SCHEMBL17880393 0.85 NPC1 (0.38) CYP3A4ALDH1A1CYP1A2KDM4EHPGD
SCHEMBL16483670 0.85 CYP11B1 (0.52) CYP11B1CYP11B2CYP19A1CYP17A1PGR
SCHEMBL16483785 0.85 CYP2A6 (0.53) CYP11B1CYP11B2CYP19A1CYP17A1PGR
SCHEMBL16483037 0.85 CYP2A6 (0.53) CYP11B1CYP11B2CYP19A1CYP17A1PGR
SCHEMBL16483095 0.85 CYP11B1 (0.49) CYP11B1CYP11B2CYP19A1CYP17A1PGR
SCHEMBL15447017 0.85 CYP11B1 (0.50) CYP11B1CYP11B2CYP19A1CYP17A1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9461272-B2 Organic light emitting device including light-efficiency improvement layer SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-04 US disclosed
US-9461272-B2 Organic light emitting device including light-efficiency improvement layer SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-04 US disclosed
US-20160190516-A1 ORGANIC LIGHT EMITTING DEVICE INCLUDING LIGHT-EFFICIENCY IMPROVEMENT LAYER SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-30 US disclosed
US-20160190516-A1 ORGANIC LIGHT EMITTING DEVICE INCLUDING LIGHT-EFFICIENCY IMPROVEMENT LAYER SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-30 US disclosed