SCHEMBL17880397

SCHEMBL17880397

Brc1cc(-c2ccccn2)cc(-c2ccc3ccc4cccc5ccc2c3c45)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 2/20 0.41
TGFBR1 P36897 1/20 0.37
KDM4E B2RXH2 7/20 0.37
SMN1; SMN2 Q16637 4/20 0.37
LMNA P02545 4/20 0.37
TP53 P04637 3/20 0.37
MAPK1 P28482 2/20 0.37
CCR1 P32246 2/20 0.37
CCR5 P51681 2/20 0.37
CCR8 P51685 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
ALPL P05186 1/20 0.37
HSP90AA1 P07900 1/20 0.37
ALPI P09923 1/20 0.37
ALPG P10696 1/20 0.37
ALOX15 P16050 1/20 0.37
HTT P42858 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MAPT P10636 3/20 0.36
ALDH1A1 P00352 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17427674 0.93 KDM4E (0.42) TGFBR1KDM4ESMN1; SMN2LMNATP53
SCHEMBL16557791 0.86 CYP1A2 (0.39) GRM5TGFBR1KDM4ESMN1; SMN2LMNA
SCHEMBL16484807 0.86 KDM4E (0.41) GRM5TGFBR1KDM4ESMN1; SMN2LMNA
SCHEMBL16483027 0.86 KDM4E (0.39) GRM5TGFBR1KDM4ESMN1; SMN2LMNA
SCHEMBL16483791 0.86 KDM4E (0.39) GRM5TGFBR1KDM4ESMN1; SMN2LMNA
SCHEMBL17880396 0.85 MEN1 (0.43) KDM4EMAPK1TDP1L3MBTL1MAPT
SCHEMBL17880394 0.85 GUSB (0.37) GRM5TGFBR1KDM4ELMNAMAPT
SCHEMBL15447014 0.85 KDM4E (0.42) TGFBR1KDM4ESMN1; SMN2LMNATP53
SCHEMBL16483748 0.85 DHODH (0.42) KDM4ESMN1; SMN2LMNATP53MAPK1
SCHEMBL16483777 0.85 DHODH (0.42) KDM4ESMN1; SMN2LMNATP53MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9461272-B2 Organic light emitting device including light-efficiency improvement layer SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-04 US disclosed
US-9461272-B2 Organic light emitting device including light-efficiency improvement layer SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-04 US disclosed
US-20160190516-A1 ORGANIC LIGHT EMITTING DEVICE INCLUDING LIGHT-EFFICIENCY IMPROVEMENT LAYER SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-30 US disclosed
US-20160190516-A1 ORGANIC LIGHT EMITTING DEVICE INCLUDING LIGHT-EFFICIENCY IMPROVEMENT LAYER SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-30 US disclosed