Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17874243 | 0.99 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL17874250 | 0.81 | PDE3B (0.44) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL15648504 | 0.78 | PDE3B (0.45) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL1694437 | 0.76 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL15175029 | 0.76 | PDE3B (0.44) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL16344943 | 0.76 | KDM4E (0.36) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL15709836 | 0.75 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL15648703 | 0.75 | KDM4E (0.51) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL17874296 | 0.75 | KDM4E (0.36) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL17887386 | 0.74 | EZH2 (0.44) | KDM4EALDH1A1MAPTGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016102493-A1 | IMIDAZOPYRIDINE EZH2 INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-06-30 | — | — | WO | disclosed |