Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 18/20 | 0.81 |
| ▸ | KDM1A | O60341 | 1/20 | 0.56 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.56 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17890286 | 1.00 | FLT3 (0.81) | FLT3KDM1AEHMT2RCOR1 | |
| SCHEMBL17890175 | 0.91 | FLT3 (0.76) | FLT3 | |
| SCHEMBL17890178 | 0.91 | FLT3 (0.76) | FLT3 | |
| SCHEMBL17890197 | 0.90 | FLT3 (0.82) | FLT3 | |
| SCHEMBL17890194 | 0.90 | FLT3 (0.82) | FLT3 | |
| SCHEMBL17890145 | 0.90 | FLT3 (1.00) | FLT3 | |
| SCHEMBL17890142 | 0.90 | FLT3 (1.00) | FLT3 | |
| SCHEMBL17890086 | 0.87 | FLT3 (0.74) | FLT3 | |
| SCHEMBL17890089 | 0.87 | FLT3 (0.74) | FLT3 | |
| SCHEMBL17890317 | 0.87 | FLT3 (1.00) | FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951029-B2 | Styryl quinazoline derivatives as pharmaceutically active agents | VICHEM CHEMIE KUTATÓ KFT. (HU) | 2018-04-24 | — | — | US | disclosed |
| US-20160194291-A1 | STYRYL QUINAZOLINE DERIVATIVES AS PHARMACEUTICALLY ACTIVE AGENTS | VICHEM CHEMIE KUTATÓ KFT. (HU) | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160194291-A1 | STYRYL QUINAZOLINE DERIVATIVES AS PHARMACEUTICALLY ACTIVE AGENTS | FLT3, BCR, STK3 | FLT3 1/4885KDM1A 4177/4885EHMT2 4385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.