Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.74 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.74 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.74 |
| ▸ | PPARG | P37231 | 7/20 | 0.74 |
| ▸ | PPARD | Q03181 | 7/20 | 0.74 |
| ▸ | PPARA | Q07869 | 7/20 | 0.74 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.74 |
| ▸ | TSHR | P16473 | 4/20 | 0.74 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | TLR2 | O60603 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
| ▸ | FABP4 | P15090 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.74 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | ESR1 | P03372 | 1/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | PDE4A | P27815 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL11453017 | 1.00 | FFAR4 (0.74) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL5710166 | 1.00 | FFAR4 (0.74) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL775625 | 1.00 | FFAR4 (0.74) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL12504620 | 1.00 | FFAR4 (0.74) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL20943305 | 1.00 | FFAR4 (0.74) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL25195763 | 1.00 | FFAR4 (0.74) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL9626178 | 1.00 | FFAR4 (0.74) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL10592536 | 1.00 | FFAR4 (0.74) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL10780484 | 1.00 | FFAR4 (0.74) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL2492074 | 1.00 | FFAR4 (0.74) | FFAR4FFAR1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120128763-A1 | LUBRICANT FOR THE OCULAR SURFACE | MELBJ HOLDINGS, LLC | 2012-05-24 | — | — | US | claimed |
| EP-1727565-A2 | LUBRICANT FOR THE OCULAR SURFACE | Melbj Holdings, LLC (US) | 2006-12-06 | — | — | EP | claimed |
| WO-2006004577-A2 | LUBRICANT FOR THE OCULAR SURFACE | MELBJ HOLDINGS, LLC (US) | 2006-01-12 | — | — | WO | claimed |
| US-20050202097-A1 | Lubricant for the ocular surface | MELBJ HOLDINGS, LLC, FLORIDA | 2005-09-15 | — | — | US | claimed |
| US-12220439-B2 | Methods of diagnosing and treating dry eye syndrome and compositions for treating a human eye | AKRIVISTA LLC (US) | 2025-02-11 | — | — | US | disclosed |
| US-11903986-B2 | Methods of diagnosing and treating dry eye syndrome and compositions for treating a human eye | AKRIVISTA LLC (US) | 2024-02-20 | — | — | US | disclosed |
| US-20230233637-A1 | METHODS OF DIAGNOSING AND TREATING DRY EYE SYNDROME AND COMPOSITIONS FOR TREATING A HUMAN EYE | AKRIVISTA LLC | 2023-07-27 | — | — | US | disclosed |
| US-11622982-B2 | Methods of diagnosing and treating dry eye syndrome and compositions for treating a human eye | AKRIVISTA LLC (US) | 2023-04-11 | — | — | US | disclosed |
| EP-3668474-A1 | METHODS OF DIAGNOSING AND TREATING DRY EYE SYNDROME AND COMPOSITIONS FOR TREATING A HUMAN EYE | Akrivista, LLC (US) | 2020-06-24 | — | — | EP | disclosed |
| US-20200164013-A1 | METHODS OF DIAGNOSING AND TREATING DRY EYE SYNDROME AND COMPOSITIONS FOR TREATING A HUMAN EYE | AKRIVISTA LLC | 2020-05-28 | — | — | US | disclosed |
| EP-3500344-A1 | METHODS OF DIAGNOSING AND TREATING DRY EYE SYNDROME AND COMPOSITIONS FOR TREATING A HUMAN EYE | Akrivista, LLC (US) | 2019-06-26 | — | — | EP | disclosed |
| WO-2019036625-A1 | METHODS OF DIAGNOSING AND TREATING DRY EYE SYNDROME AND COMPOSITIONS FOR TREATING A HUMAN EYE | Akrivista, LLC (US) | 2019-02-21 | — | — | WO | disclosed |
| WO-2014035451-A1 | OPHTHALMIC COMPOSITIONS WITH WAX ESTERS | BAUSCH & LOMB INCORPORATED (US) | 2014-03-06 | — | — | WO | disclosed |
| US-8455016-B2 | Treatment for meibomian gland dysfunction or obstruction | MELBJ HOLDINGS, LLC (US) | 2013-06-04 | — | — | US | disclosed |
| US-20130131171-A1 | Treatment for Meibomian Gland Dysfunction or Obstruction | MELBJ HOLDINGS, LLC (US) | 2013-05-23 | — | — | US | disclosed |
| US-20120128763-A1 | LUBRICANT FOR THE OCULAR SURFACE | MELBJ HOLDINGS, LLC | 2012-05-24 | — | — | US | disclosed |
| US-20110124725-A1 | Treatment for Meibomian Gland Dysfunction or Obstruction | MELBJ HOLDINGS, LLC | 2011-05-26 | — | — | US | disclosed |
| EP-1727565-A2 | LUBRICANT FOR THE OCULAR SURFACE | Melbj Holdings, LLC (US) | 2006-12-06 | — | — | EP | disclosed |
| WO-2006004577-A2 | LUBRICANT FOR THE OCULAR SURFACE | MELBJ HOLDINGS, LLC (US) | 2006-01-12 | — | — | WO | disclosed |
| US-20050202097-A1 | Lubricant for the ocular surface | MELBJ HOLDINGS, LLC, FLORIDA | 2005-09-15 | — | — | US | disclosed |