SCHEMBL17892811

SCHEMBL17892811

COC(=O)C1(C(=O)O)CCCC(C)C1

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.45
NPSR1 Q6W5P4 1/20 0.34
MAPT P10636 1/20 0.33
ALDH1A1 P00352 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KDM4E B2RXH2 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28983033 0.91 CYP1A2 (0.44) CYP1A2NPSR1MAPTALDH1A1L3MBTL1
SCHEMBL17892423 0.89 CYP1A2 (0.36) CYP1A2NPSR1MAPTALDH1A1L3MBTL1
SCHEMBL632817 0.88 CYP1A2 (0.46) CYP1A2ALDH1A1KDM4ETDP1
SCHEMBL27851170 0.86 CYP1A2 (0.35) CYP1A2NPSR1ALDH1A1KDM4E
SCHEMBL15859172 0.85 CYP1A2 (0.53) CYP1A2TDP1
Hydrochloric Acid SCHEMBL27282843 0.81 CYP1A2 (0.44) CYP1A2MAPTALDH1A1KDM4ETDP1
SCHEMBL30683846 0.80 NPSR1 (0.35) CYP1A2NPSR1MAPTALDH1A1L3MBTL1
SCHEMBL4006703 0.78 NPSR1 (0.34) CYP1A2NPSR1MAPT
SCHEMBL757321 0.77 NPSR1 (0.48) NPSR1MAPTALDH1A1L3MBTL1
SCHEMBL230257 0.77 NPSR1 (0.43) NPSR1MAPTALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115532255-A Preparation method and application of Ru-based catalyst 厦门大学 2022-12-30 CN disclosed
CN-111302929-B Catalyst for aqueous phase catalytic hydrogenation of phthalic acids and ester derivatives thereof, preparation method and application 华侨大学 2022-11-01 CN disclosed
US-10597344-B2 Method for preparing 1,3-cyclohexanedimethanol LOTTE CHEMICAL CORPORATION (KR) 2020-03-24 US disclosed
EP-3511313-A1 METHOD FOR PREPARING 1,3-CYCLOHEXANEDIMETHANOL Lotte Chemical Corporation (KR) 2019-07-17 EP disclosed
US-20190202761-A1 METHOD FOR PREPARING 1,3-CYCLOHEXANEDIMETHANOL LOTTE CHEMICAL CORPORATION (KR) 2019-07-04 US disclosed
WO-2016106652-A1 BIARYLETHER IMIDAZOPYRAZINE BTK INHIBITORS MERCK SHARP & DOHME CORP. (US) 2016-07-07 WO disclosed