Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.36 |
| ▸ | IKBKB | O14920 | 8/20 | 0.36 |
| ▸ | CHUK | O15111 | 5/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17895179 | 0.86 | IKBKB (0.39) | MIFADORA2AADORA3IKBKBCHUK | |
| SCHEMBL17895297 | 0.85 | ADORA2A (0.43) | MIFADORA2AADORA3IKBKBCHUK | |
| SCHEMBL17895231 | 0.85 | MIF (0.37) | MIFIKBKBCHUK | |
| SCHEMBL17895092 | 0.85 | MIF (0.37) | MIFIKBKBCHUK | |
| SCHEMBL17895305 | 0.85 | IKBKB (0.38) | MIFIKBKBCHUK | |
| SCHEMBL17895202 | 0.84 | BRD4 (0.39) | MIFIKBKBCHUK | |
| SCHEMBL22099669 | 0.83 | LCK (0.37) | MIFIKBKBCHUK | |
| SCHEMBL17895225 | 0.83 | BRD4 (0.42) | MIFIKBKBCHUK | |
| SCHEMBL17895199 | 0.82 | IKBKB (0.46) | MIFADORA2AIKBKBCHUKADORA1 | |
| SCHEMBL17895189 | 0.80 | IKBKB (0.47) | MIFIKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240789-B1 | NEW IMIDAZO[1,2-A]QUINOXALINES AND DERIVATES THEREOF FOR THE TREATMENT OF CANCER | UNIV MONTPELLIER (FR) | 2020-07-29 | — | — | EP | claimed |
| EP-3240789-A1 | NEW IMIDAZO[1,2-A]QUINOXALINES AND DERIVATES THEREOF FOR THE TREATMENT OF CANCER | Université de Montpellier (FR) | 2017-11-08 | — | — | EP | claimed |
| WO-2016107895-A1 | NEW IMIDAZO[1,2-A]QUINOXALINES AND DERIVATES THEREOF FOR THE TREATMENT OF CANCER | UNIVERSITE DE MONTPELLIER (FR) | 2016-07-07 | — | — | WO | claimed |
| EP-3240789-B1 | NEW IMIDAZO[1,2-A]QUINOXALINES AND DERIVATES THEREOF FOR THE TREATMENT OF CANCER | UNIV MONTPELLIER (FR) | 2020-07-29 | — | — | EP | disclosed |
| EP-3240789-A1 | NEW IMIDAZO[1,2-A]QUINOXALINES AND DERIVATES THEREOF FOR THE TREATMENT OF CANCER | Université de Montpellier (FR) | 2017-11-08 | — | — | EP | disclosed |
| WO-2016107895-A1 | NEW IMIDAZO[1,2-A]QUINOXALINES AND DERIVATES THEREOF FOR THE TREATMENT OF CANCER | UNIVERSITE DE MONTPELLIER (FR) | 2016-07-07 | — | — | WO | disclosed |