Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19770379 | 0.95 | HRH1 (0.95) | HRH1KCNH2 | |
| SCHEMBL19770377 | 0.94 | HRH1 (0.85) | HRH1KCNH2 | |
| SCHEMBL19770376 | 0.93 | HRH1 (0.91) | HRH1KCNH2 | |
| SCHEMBL17898450 | 0.93 | HRH1 (1.00) | HRH1KCNH2 | |
| SCHEMBL17888843 | 0.91 | HRH1 (1.00) | HRH1KCNH2 | |
| SCHEMBL30306737 | 0.91 | HRH1 (0.83) | HRH1KCNH2 | |
| SCHEMBL17888850 | 0.91 | HRH1 (1.00) | HRH1KCNH2 | |
| SCHEMBL17888858 | 0.90 | HRH1 (1.00) | HRH1KCNH2 | |
| SCHEMBL14198337 | 0.89 | HRH1 (0.80) | HRH1KCNH2 | |
| SCHEMBL19770373 | 0.88 | HRH1 (0.82) | HRH1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180016251-A1 | NEW BENZIMIDAZOLE DERIVATIVES AS ANTIHISTAMINE AGENTS | FAES FARMA, S.A. (ES) | 2018-01-18 | — | — | US | disclosed |
| EP-3240783-A1 | NEW BENZIMIDAZOLE DERIVATIVES AS ANTIHISTAMINE AGENTS | FAES FARMA, S.A. (ES) | 2017-11-08 | — | — | EP | disclosed |
| WO-2016107848-A1 | NEW BENZIMIDAZOLE DERIVATIVES AS ANTIHISTAMINE AGENTS | FAES FARMA, S.A. (ES) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180016251-A1 | NEW BENZIMIDAZOLE DERIVATIVES AS ANTIHISTAMINE AGENTS | HRH2, HRH4, HRH1 | HRH1 3/4885KCNH2 381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.