Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17895839 | 0.80 | PLK1 (0.47) | PLK1CSNK2A1PLK3 | |
| SCHEMBL17895885 | 0.77 | PLK1 (0.36) | PLK1CSNK2A1PLK3 | |
| SCHEMBL17895994 | 0.77 | PLK1 (0.36) | PLK1CSNK2A1PLK3 | |
| SCHEMBL17895983 | 0.77 | PLK1 (0.36) | PLK1CSNK2A1PLK3 | |
| SCHEMBL17495175 | 0.72 | — | — | |
| SCHEMBL17498127 | 0.72 | KCNA3 (0.33) | — | |
| SCHEMBL17498147 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL17495121 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL17498115 | 0.72 | KCNA3 (0.32) | — | |
| SCHEMBL17495027 | 0.71 | DAO (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | claimed |
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | disclosed |