Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11581346 | 0.78 | SMN1; SMN2 (0.53) | KDM4EGAAKMT2ALMNAALDH1A1 | |
| SCHEMBL10751781 | 0.77 | PI4KA (0.50) | KDM4EGAAKMT2ALMNAADORA2A | |
| SCHEMBL14564418 | 0.77 | MAPT (0.52) | KDM4EGAAKMT2ALMNAALDH1A1 | |
| SCHEMBL10510446 | 0.75 | PI4KA (0.44) | KDM4EGAAKMT2AADORA3LMNA | |
| SCHEMBL1108399 | 0.74 | EGFR (0.53) | LMNAADORA2AALDH1A1PI4KAPI4K2B | |
| SCHEMBL2614518 | 0.73 | PI4KA (0.50) | GAAKMT2ALMNAADORA2AALDH1A1 | |
| SCHEMBL160405 | 0.73 | PI4KA (0.55) | GAAKMT2ALMNAADORA2AALDH1A1 | |
| SCHEMBL3822880 | 0.73 | PI4KA (0.50) | GAAKMT2ALMNAADORA2AALDH1A1 | |
| SCHEMBL11728330 | 0.73 | PI4KA (0.55) | GAAKMT2ALMNAADORA2AALDH1A1 | |
| SCHEMBL5456634 | 0.73 | CYP1A2 (0.67) | KDM4EKMT2ALMNAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109360-A1 | DIHYDROQUINAZOLINE INHIBITORS OF VIRAL TERMINASE | AUSPEX PHARMACEUTICALS, INC. (US) | 2016-07-07 | — | — | WO | disclosed |