Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.57 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.57 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CD69 | Q07108 | 1/20 | 0.52 |
| ▸ | B4GALT1 | P15291 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16628272 | 1.00 | MAPK1 (0.81) | MAPK1ALDH1A1THRBCA1CA2 | |
| SCHEMBL26167578 | 1.00 | MAPK1 (0.81) | MAPK1ALDH1A1THRBCA1CA2 | |
| SCHEMBL23968747 | 1.00 | MAPK1 (0.81) | MAPK1ALDH1A1THRBCA1CA2 | |
| SCHEMBL16690927 | 1.00 | MAPK1 (0.81) | MAPK1ALDH1A1THRBCA1CA2 | |
| SCHEMBL27333328 | 0.92 | MAPK1 (0.74) | MAPK1ALDH1A1THRBCA1CA2 | |
| SCHEMBL18660816 | 0.92 | MAPK1 (0.74) | MAPK1ALDH1A1THRBCA1CA2 | |
| SCHEMBL17505984 | 0.92 | MAPK1 (0.74) | MAPK1ALDH1A1THRBCA1CA2 | |
| SCHEMBL22461938 | 0.92 | MAPK1 (0.74) | MAPK1ALDH1A1THRBCA1CA2 | |
| SCHEMBL14903046 | 0.92 | MAPK1 (0.74) | MAPK1ALDH1A1THRBCA1CA2 | |
| SCHEMBL13786399 | 0.92 | MAPK1 (0.90) | MAPK1ALDH1A1THRBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017174657-A1 | NUCLEIC ACID LINKED TO A TRIVALENT GLYCOCONJUGATE | SILENCE THERAPEUTICS GMBH (DE) | 2017-10-12 | — | — | WO | disclosed |
| US-9382540-B2 | Compositions and methods for modulating angiopoietin-like 3 expression | ISIS PHARMACEUTICALS, INC (US) | 2016-07-05 | — | — | US | disclosed |