SCHEMBL17897142

SCHEMBL17897142

CC(=O)NC1[C@H](OCCCCCN)OC(CO[C@]2(C(=O)O)C[C@@H](O)[C@@H](C)C([C@H](O)[C@H](O)CO)O2)[C@@H](O)[C@@H]1O

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SIGLEC7 Q9Y286 6/20 0.59
▸ MAG P20916 4/20 0.49
▸ MAPK1 P28482 1/20 0.43
▸ CD22 P20273 6/20 0.43
▸ SELL P14151 1/20 0.43
▸ SELP P16109 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17889795 0.94 SIGLEC7 (0.66) SIGLEC7MAGCD22SELLSELP
SCHEMBL17897325 0.94 SIGLEC7 (0.66) SIGLEC7MAGCD22SELLSELP
SCHEMBL17897145 0.92 SIGLEC7 (0.63) SIGLEC7MAGSELLSELP
SCHEMBL17897134 0.92 SIGLEC7 (0.63) SIGLEC7MAGSELLSELP
SCHEMBL20193276 0.90 SIGLEC7 (0.66) SIGLEC7MAGCD22SELLSELP
SCHEMBL16377870 0.90 SIGLEC7 (0.66) SIGLEC7MAGCD22SELLSELP
SCHEMBL17897148 0.88 SIGLEC7 (0.65) SIGLEC7MAGSELLSELP
SCHEMBL17889797 0.86 SIGLEC7 (0.69) SIGLEC7MAGSELLSELP
SCHEMBL21043889 0.86 SIGLEC7 (0.69) SIGLEC7MAGSELLSELP
SCHEMBL21043890 0.86 SIGLEC7 (0.69) SIGLEC7MAGSELLSELP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160193310-A1 RM2 ANTIGENS AND USE THEREOF ACADEMIA SINICA 2016-07-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160193310-A1 RM2 ANTIGENS AND USE THEREOF LGALS2, MAN2B2, GALNT2 SIGLEC7 6/4885MAG 74/4885MAPK1 3387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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