Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 3/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19091082 | 0.89 | TSHR (0.40) | TSHRPTPN1ALDH1A1SPHK1MGAM | |
| SCHEMBL9656469 | 0.85 | TSHR (0.38) | TSHRPTPN1ALDH1A1MGAMUSP2 | |
| SCHEMBL6229989 | 0.84 | TSHR (0.41) | TSHRALDH1A1SPHK1MGAMUSP2 | |
| SCHEMBL14416994 | 0.81 | TSHR (0.34) | TSHR | |
| SCHEMBL15694926 | 0.80 | TSHR (0.33) | TSHR | |
| SCHEMBL17663532 | 0.80 | TSHR (0.39) | TSHRALDH1A1SPHK1USP2HTT | |
| SCHEMBL27639245 | 0.79 | TSHR (0.39) | TSHRPTPN1ALDH1A1SPHK1MGAM | |
| SCHEMBL8599978 | 0.79 | TSHR (0.39) | TSHRSPHK1USP2MEN1THRB | |
| SCHEMBL13497241 | 0.78 | TSHR (0.47) | TSHRSPHK1USP2MEN1THRB | |
| SCHEMBL9656415 | 0.78 | PTPN1 (0.47) | TSHRPTPN1ALDH1A1SPHK1MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109291-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109290-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |