Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17899062 | 0.92 | SCN9A (0.36) | KMT2AL3MBTL1GAAKDM1AMAOB | |
| SCHEMBL16605387 | 0.90 | KMT2A (0.38) | CACNA1GKMT2AL3MBTL1 | |
| SCHEMBL17898811 | 0.88 | GAA (0.38) | KMT2AL3MBTL1GAAKDM1AMAOB | |
| SCHEMBL15370900 | 0.87 | KMT2A (0.39) | KMT2AL3MBTL1GAAKDM1AMAOB | |
| SCHEMBL19628419 | 0.84 | TP53 (0.34) | CACNA1GKMT2AL3MBTL1KDM1AMAOB | |
| SCHEMBL16605405 | 0.83 | KMT2A (0.43) | KMT2AL3MBTL1KDM1AMAOB | |
| SCHEMBL17898805 | 0.83 | KMT2A (0.41) | KMT2AL3MBTL1KDM1AMAOB | |
| SCHEMBL17903383 | 0.82 | KMT2A (0.37) | KMT2AL3MBTL1GAAKDM1AMAOB | |
| SCHEMBL16604080 | 0.82 | KMT2A (0.38) | KMT2AL3MBTL1KDM1AMAOB | |
| SCHEMBL16605382 | 0.81 | KMT2A (0.38) | KMT2AL3MBTL1KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109291-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109290-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |