Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.32 |
| ▸ | SKP1 | P63208 | 1/20 | 0.32 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17899057 | 0.94 | GAA (0.35) | GAAKDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL17898879 | 0.91 | GAA (0.39) | GAAKDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL17898712 | 0.90 | KDM1A (0.36) | GAAKDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL17899056 | 0.89 | GAA (0.34) | GAAKDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL17898915 | 0.89 | GAA (0.34) | GAAKDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL19628412 | 0.88 | GAA (0.41) | GAAKDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL17899059 | 0.86 | GAA (0.38) | GAAKDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL17898908 | 0.86 | GAA (0.39) | GAAKDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL17898714 | 0.85 | KDM1A (0.36) | GAAKDM1AMAOBKMT2AL3MBTL1 | |
| SCHEMBL17898911 | 0.84 | GAA (0.34) | GAAKDM1AMAOBKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109290-A1 | MACROCYCLIC PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109291-A1 | USE OF MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |