Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 14/20 | 0.42 |
| ▸ | PDE4A | P27815 | 7/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.38 |
| ▸ | ATF4 | P18848 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 3/20 | 0.36 |
| ▸ | F10 | P00742 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.36 |
| ▸ | F7 | P08709 | 3/20 | 0.36 |
| ▸ | F3 | P13726 | 3/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17888571 | 0.87 | PDE4D (0.40) | PDE4DPDE4APDE4BPDE4CPARP10 | |
| SCHEMBL17888568 | 0.87 | PDE4D (0.40) | PDE4DPDE4APDE4BPDE4CPARP10 | |
| SCHEMBL17888576 | 0.87 | PDE4D (0.40) | PDE4DPDE4APDE4BPDE4CPARP10 | |
| SCHEMBL17899141 | 0.86 | PDE4D (0.42) | PDE4DPDE4APDE4BPDE4CPARP10 | |
| SCHEMBL20525479 | 0.86 | PDE4D (0.42) | PDE4DPDE4APDE4BPDE4CPARP10 | |
| SCHEMBL17888652 | 0.86 | PDE4D (0.42) | PDE4DPDE4APDE4BPDE4CPARP10 | |
| SCHEMBL17888650 | 0.86 | PDE4D (0.42) | PDE4DPDE4APDE4BPDE4CPARP10 | |
| SCHEMBL17931464 | 0.86 | PDE4D (0.42) | PDE4DPDE4APDE4BPDE4CPARP10 | |
| SCHEMBL17899388 | 0.86 | PDE4D (0.42) | PDE4DPDE4APDE4BPDE4CPARP10 | |
| SCHEMBL17888598 | 0.81 | PARP10 (0.38) | PDE4DPDE4APDE4BPDE4CPARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3040329-A1 | NOVEL AROMATIC COMPOUND AND USE THEREOF | Kyoto Pharmaceutical Industries, Ltd. (JP) | 2016-07-06 | — | — | EP | disclosed |