SCHEMBL17899559

SCHEMBL17899559

COc1cc(/C=C2\CN(C)C/C(=C\c3cc(OC)c(OC)c(OC)c3)C2=O)cc(OC)c1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LY96 Q9Y6Y9 2/20 1.00
SMN1; SMN2 Q16637 5/20 0.71
LMNA P02545 4/20 0.71
HSD17B3 P37058 1/20 0.68
MAPT P10636 6/20 0.66
ALDH1A1 P00352 5/20 0.66
NPC1 O15118 3/20 0.66
RAB9A P51151 2/20 0.66
ATM Q13315 2/20 0.66
XBP1 P17861 2/20 0.66
MAPK1 P28482 2/20 0.66
PKM P14618 1/20 0.66
PAX8 Q06710 1/20 0.66
NPSR1 Q6W5P4 1/20 0.66
TDP1 Q9NUW8 1/20 0.66
MEN1 O00255 4/20 0.64
KMT2A Q03164 4/20 0.64
NFE2L2 Q16236 1/20 0.61
NOD2 Q9HC29 1/20 0.59
KDM4E B2RXH2 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25842377 0.91 LY96 (0.82) LY96SMN1; SMN2LMNAHSD17B3MAPT
SCHEMBL14597262 0.84 LY96 (0.72) LY96SMN1; SMN2LMNAHSD17B3MAPT
SCHEMBL17899535 0.84 LY96 (0.72) LY96SMN1; SMN2LMNAHSD17B3MAPT
SCHEMBL22822872 0.83 MAPT (0.72) LY96SMN1; SMN2LMNAMAPTALDH1A1
SCHEMBL17899519 0.81 HSD17B3 (1.00) LY96SMN1; SMN2LMNAHSD17B3MAPT
SCHEMBL22823103 0.81 SMN1; SMN2 (0.76) LY96SMN1; SMN2LMNAHSD17B3MAPT
SCHEMBL22462348 0.80 LY96 (0.67) LY96SMN1; SMN2LMNAHSD17B3MAPT
SCHEMBL22462349 0.80 LY96 (0.67) LY96SMN1; SMN2LMNAHSD17B3MAPT
SCHEMBL22822756 0.80 LY96 (0.67) LY96SMN1; SMN2LMNAHSD17B3MAPT
SCHEMBL31686199 0.80 LY96 (0.67) LY96SMN1; SMN2LMNAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025106009-A1 SYNCHRONIZATION BETWEEN A COMMUNICATION DEVICE AND A NETWORK UPON COMMUNICATION DEVICE AUTONOMOUS RELEASE OF A QUALITY OF EXPERIENCE CONFIGURATION TELEFONAKTIEBOLAGET LM ERICSSON (PUBL) (SE) 2025-05-22 WO disclosed
US-20250060518-A1 NANOPARTICLE FILM PATTERNING METHOD, METHOD FOR PRODUCING LIGHT-EMITTING ELEMENT, METHOD FOR PRODUCING DISPLAY DEVICE, AND LIGHT-EMITTING ELEMENT SHARP KABUSHIKI KAISHA (JP) 2025-02-20 US disclosed
US-12197062-B2 Liquid crystal composition for light-scattering liquid crystal device, light-scattering liquid crystal device, and smart window DIC CORPORATION (JP) 2025-01-14 US disclosed
CN-117581636-A Nanoparticle film patterning method, light-emitting element manufacturing method, display device manufacturing method, and light-emitting element 夏普株式会社 2024-02-20 CN disclosed
US-20230357200-A1 SMALL MOLECULE STIMULATORS OF STEROID RECEPTOR COACTIVATOR-3 AND METHODS OF THEIR USE AS CARDIOPROTECTIVE AND/OR VASCULAR REGENERATIVE AGENTS BAYLOR COLLEGE OF MEDICINE (US) 2023-11-09 US disclosed
CN-219802310-U Sensor piezoelectric signal detection circuit 北京钛方科技有限责任公司 2023-10-03 CN disclosed
US-20230287272-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DEVICE DIC CORPORATION (JP) 2023-09-14 US disclosed
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound DIC CORPORATION (JP) 2023-08-29 US disclosed
EP-3823301-B1 SOUND FIELD FORMING APPARATUS AND METHOD AND PROGRAM SONY GROUP CORP (JP) 2023-08-23 EP disclosed
US-11708350-B2 Small molecule stimulators of steroid receptor coactivator-3 and methods of their use as cardioprotective and/or vascular regenerative agents BAYLOR COLLEGE OF MEDICINE (US) 2023-07-25 US disclosed
US-11326103-B2 Liquid crystal display device DIC CORPORATION (JP) 2022-05-10 US disclosed
US-20220128867-A1 SUBSTRATE AND LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2022-04-28 US disclosed
US-11312676-B2 Small molecule stimulators of steroid receptor coactivator proteins and their use in the treatment of cancer BAYLOR COLLEGE OF MEDICINE (US) 2022-04-26 US disclosed
US-11312906-B2 Polymerizable monomer, liquid crystal composition using polymerizable monomer, and liquid crystal display device DIC CORPORATION (JP) 2022-04-26 US disclosed
US-20220057672-A1 LIQUID CRYSTAL COMPOSITION FOR LIGHT-SCATTERING LIQUID CRYSTAL DEVICE, LIGHT-SCATTERING LIQUID CRYSTAL DEVICE, AND SMART WINDOW DIC CORPORATION (JP) 2022-02-24 US disclosed
US-20210115017-A1 SMALL MOLECULE STIMULATORS OF STEROID RECEPTOR COACTIVATOR-3 AND METHODS OF THEIR USE AS CARDIOPROTECTIVE AND/OR VASCULAR REGENERATIVE AGENTS BAYLOR COLLEGE OF MEDICINE (US) 2021-04-22 US disclosed
US-10875841-B2 Small molecule stimulators of steroid receptor coactivator-3 and methods of their use as cardioprotective and/or vascular regenerative agents BAYLOR COLLEGE OF MEDICINE (US) 2020-12-29 US disclosed
US-20200399220-A1 3,5-DIARYLIDENYL-N-SUBSTITUTED-PIPERID-4-ONE-DERIVED INHIBITORS OF STAT3 PATHWAY ACTIVITY AND USES THEREOF KIAKOS KONSTANTINOS (AT) 2020-12-24 US disclosed
US-20200071300-A1 Small Molecule Stimulators of Steroid Receptor Coactivator-3 and Methods of Their Use as Cardioprotective and/or Vascular Regenerative Agents BAYLOR COLLEGE OF MEDICINE (US) 2020-03-05 US disclosed
WO-2016109470-A1 SMALL MOLECULE STIMULATORS OF STEROID RECEPTOR COACTIVATOR PROTEINS AND THEIR USE IN THE TREATMENT OF CANCER BAYLOR COLLEGE OF MEDICINE (US) 2016-07-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11739270-B2 Polymerizable compound as well as liquid crystal composition and liquid crystal display device each including polymerizable compound OCIAD2, PKN2, SKP1 LY96 1665/4885SMN1; SMN2 3918/4885LMNA 3654/4885
US-20200071300-A1 Small Molecule Stimulators of Steroid Receptor Coactivator-3 and Methods of Their Use as Cardioprotective and/or Vascular Regenerative Agents NCOA3, FABP3, NCOA1 LY96 1393/4885SMN1; SMN2 3684/4885LMNA 2223/4885
US-11312676-B2 Small molecule stimulators of steroid receptor coactivator proteins and their use in the treatment of cancer NCOA2, NCOA1, NCOA3 LY96 1243/4885SMN1; SMN2 4722/4885LMNA 4287/4885
US-20210115017-A1 SMALL MOLECULE STIMULATORS OF STEROID RECEPTOR COACTIVATOR-3 AND METHODS OF THEIR USE AS CARDIOPROTECTIVE AND/OR VASCULAR REGENERATIVE AGENTS NCOA3, FABP3, NCOA1 LY96 1393/4885SMN1; SMN2 3684/4885LMNA 2223/4885
US-11708350-B2 Small molecule stimulators of steroid receptor coactivator-3 and methods of their use as cardioprotective and/or vascular regenerative agents NCOA3, FABP3, NCOA1 LY96 1393/4885SMN1; SMN2 3684/4885LMNA 2223/4885
US-10875841-B2 Small molecule stimulators of steroid receptor coactivator-3 and methods of their use as cardioprotective and/or vascular regenerative agents NCOA3, FABP3, NCOA1 LY96 1393/4885SMN1; SMN2 3684/4885LMNA 2223/4885
US-20200399220-A1 3,5-DIARYLIDENYL-N-SUBSTITUTED-PIPERID-4-ONE-DERIVED INHIBITORS OF STAT3 PATHWAY ACTIVITY AND USES THEREOF STAT3, JAK2, STAT6 LY96 1163/4885SMN1; SMN2 4073/4885LMNA 3396/4885
US-20230357200-A1 SMALL MOLECULE STIMULATORS OF STEROID RECEPTOR COACTIVATOR-3 AND METHODS OF THEIR USE AS CARDIOPROTECTIVE AND/OR VASCULAR REGENERATIVE AGENTS NCOA3, FABP3, NCOA1 LY96 1393/4885SMN1; SMN2 3684/4885LMNA 2223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.