Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDUA | P35475 | 1/20 | 0.47 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FGF2 | P09038 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SELP | P16109 | 2/20 | 0.32 |
| ▸ | SELL | P14151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13969565 | 1.00 | IDUA (0.47) | IDUASUCNR1CA9CA12CA2 | |
| SCHEMBL13377847 | 1.00 | IDUA (0.47) | IDUASUCNR1CA9CA12CA2 | |
| SCHEMBL8340283 | 1.00 | IDUA (0.47) | IDUASUCNR1CA9CA12CA2 | |
| SCHEMBL19848245 | 1.00 | IDUA (0.47) | IDUASUCNR1CA9CA12CA2 | |
| SCHEMBL13478556 | 1.00 | IDUA (0.47) | IDUASUCNR1CA9CA12CA2 | |
| SCHEMBL15473351 | 1.00 | IDUA (0.47) | IDUASUCNR1CA9CA12CA2 | |
| SCHEMBL23502390 | 1.00 | IDUA (0.47) | IDUASUCNR1CA9CA12CA2 | |
| SCHEMBL13887430 | 1.00 | IDUA (0.47) | IDUASUCNR1CA9CA12CA2 | |
| SCHEMBL20800901 | 1.00 | IDUA (0.47) | IDUASUCNR1CA9CA12CA2 | |
| SCHEMBL749480 | 1.00 | IDUA (0.47) | IDUASUCNR1CA9CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016108587-A1 | REPEBODY DERIVATIVE-DRUG CONJUGATE, PREPARATION METHOD AND USE THEREOF | 주식회사 레고켐 바이오사이언스 | 2016-07-07 | — | — | WO | disclosed |