Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 8/20 | 0.43 |
| ▸ | ATM | Q13315 | 7/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.38 |
| ▸ | PRKDC | P78527 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | NRP1 | O14786 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17821027 | 0.91 | PIK3C3 (0.46) | PIK3C3ATMPIK3CAPRKDCALDH1A1 | |
| SCHEMBL17819992 | 0.89 | PIK3C3 (0.44) | PIK3C3ATMPIK3CAPRKDCALDH1A1 | |
| SCHEMBL17820067 | 0.89 | PIK3C3 (0.44) | PIK3C3ATMPIK3CAPRKDCALDH1A1 | |
| SCHEMBL17828046 | 0.89 | PIK3C3 (0.44) | PIK3C3ATMPIK3CAPRKDCALDH1A1 | |
| SCHEMBL17820003 | 0.88 | PIK3C3 (0.43) | PIK3C3ATMPIK3CAPRKDCALDH1A1 | |
| SCHEMBL17820622 | 0.88 | PIK3C3 (0.43) | PIK3C3ATMPIK3CAPRKDCALDH1A1 | |
| SCHEMBL17819457 | 0.88 | PIK3C3 (0.48) | PIK3C3ATMPIK3CAPRKDCALDH1A1 | |
| SCHEMBL17821018 | 0.88 | ATM (0.43) | PIK3C3ATMPIK3CAPRKDCALDH1A1 | |
| SCHEMBL17906894 | 0.87 | ATM (0.46) | PIK3C3ATMPIK3CAPRKDCALDH1A1 | |
| SCHEMBL17820398 | 0.87 | ATM (0.43) | PIK3C3ATMPIK3CAPRKDCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042900-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | Fujifilm Corporation (JP) | 2016-07-13 | — | — | EP | disclosed |