Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 5/20 | 0.46 |
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | PRKDC | P78527 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17819818 | 0.91 | ATM (0.48) | ATMPIK3C3MAPK1PRKDCPIK3CA | |
| SCHEMBL17907148 | 0.90 | ATM (0.47) | ATMPIK3C3MAPK1PRKDCPIK3CA | |
| SCHEMBL17819908 | 0.89 | ATM (0.51) | ATMPIK3C3MAPK1PRKDCPIK3CA | |
| SCHEMBL17907222 | 0.89 | ATM (0.48) | ATMPIK3C3PRKDCPIK3CAPIK3CB | |
| SCHEMBL17820608 | 0.88 | ATM (0.47) | ATMPIK3C3MAPK1PRKDCPIK3CA | |
| SCHEMBL17906628 | 0.88 | ATM (0.52) | ATMPIK3C3MAPK1PRKDCPIK3CA | |
| SCHEMBL17906836 | 0.87 | PIK3C3 (0.44) | ATMPIK3C3MAPK1PRKDCPIK3CA | |
| SCHEMBL17819729 | 0.85 | ATM (0.46) | ATMPIK3C3PRKDCPIK3CAPIK3CB | |
| SCHEMBL17906690 | 0.85 | ATM (0.48) | ATMPIK3C3PRKDCPIK3CAPIK3CB | |
| SCHEMBL17820492 | 0.85 | ATM (0.48) | ATMPIK3C3PRKDCPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042900-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | Fujifilm Corporation (JP) | 2016-07-13 | — | — | EP | disclosed |