Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 6/20 | 0.38 |
| ▸ | JAK1 | P23458 | 4/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 3/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17906836 | 0.90 | PIK3C3 (0.44) | PIK3C3ATMJAK2JAK1PRKDC | |
| SCHEMBL17906841 | 0.90 | PIK3C3 (0.40) | PIK3C3ATMJAK2JAK1PRKDC | |
| SCHEMBL17906982 | 0.89 | PIK3C3 (0.40) | PIK3C3ATMJAK2JAK1PRKDC | |
| SCHEMBL17907109 | 0.88 | PIK3C3 (0.43) | PIK3C3ATMJAK2PRKDCJAK3 | |
| SCHEMBL17820381 | 0.88 | PIK3C3 (0.40) | PIK3C3ATMPRKDCPIK3CAPIK3CB | |
| SCHEMBL17906711 | 0.87 | PIK3C3 (0.41) | PIK3C3ATMJAK2JAK1PRKDC | |
| SCHEMBL17819419 | 0.86 | PIK3C3 (0.40) | PIK3C3ATMJAK2JAK1PRKDC | |
| SCHEMBL17820983 | 0.85 | PIK3C3 (0.41) | PIK3C3ATMJAK2JAK1PRKDC | |
| SCHEMBL17820610 | 0.84 | PIK3C3 (0.41) | PIK3C3ATMJAK2JAK1PRKDC | |
| SCHEMBL17906821 | 0.84 | PIK3C3 (0.40) | PIK3C3ATMJAK2JAK1PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042900-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | Fujifilm Corporation (JP) | 2016-07-13 | — | — | EP | disclosed |