Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 14/20 | 0.46 |
| ▸ | ATM | Q13315 | 6/20 | 0.46 |
| ▸ | FLT3 | P36888 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17819894 | 0.97 | PIK3C3 (0.43) | PIK3C3ATMFLT3 | |
| SCHEMBL17819547 | 0.96 | PIK3C3 (0.44) | PIK3C3ATMFLT3LCKRET | |
| SCHEMBL17820213 | 0.94 | PIK3C3 (0.45) | PIK3C3ATMFLT3LCKRET | |
| SCHEMBL17819524 | 0.92 | PIK3C3 (0.42) | PIK3C3ATM | |
| SCHEMBL17820662 | 0.92 | PIK3C3 (0.44) | PIK3C3ATM | |
| SCHEMBL17819695 | 0.92 | PIK3C3 (0.45) | PIK3C3ATM | |
| SCHEMBL17819767 | 0.92 | PIK3C3 (0.43) | PIK3C3ATM | |
| SCHEMBL17821119 | 0.92 | PIK3C3 (0.43) | PIK3C3ATM | |
| SCHEMBL17820921 | 0.91 | PIK3C3 (0.44) | PIK3C3ATMFLT3 | |
| SCHEMBL17820919 | 0.91 | PIK3C3 (0.44) | PIK3C3ATMFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042900-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | Fujifilm Corporation (JP) | 2016-07-13 | — | — | EP | disclosed |