Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 10/20 | 0.48 |
| ▸ | ATM | Q13315 | 9/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.43 |
| ▸ | PRKDC | P78527 | 3/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17819636 | 0.95 | ATM (0.51) | PIK3C3ATMPIK3CAPRKDCPIK3CB | |
| SCHEMBL17821066 | 0.93 | ATM (0.48) | PIK3C3ATMPIK3CAPRKDCPIK3CB | |
| SCHEMBL17819772 | 0.93 | ATM (0.50) | PIK3C3ATMPIK3CAPRKDCPIK3CB | |
| SCHEMBL17820212 | 0.93 | ATM (0.49) | PIK3C3ATMPIK3CAPRKDCPIK3CB | |
| SCHEMBL17821035 | 0.93 | ATM (0.49) | PIK3C3ATMPIK3CAPRKDCPIK3CB | |
| SCHEMBL17819743 | 0.92 | PIK3C3 (0.48) | PIK3C3ATMPIK3CAPRKDCPIK3CB | |
| SCHEMBL17820361 | 0.91 | ATM (0.48) | PIK3C3ATMPIK3CAPRKDCPIK3CB | |
| SCHEMBL17820036 | 0.91 | ATM (0.46) | PIK3C3ATMPIK3CAPRKDCPIK3CB | |
| SCHEMBL17820796 | 0.91 | ATM (0.46) | PIK3C3ATMPIK3CAPRKDCPIK3CB | |
| SCHEMBL17906826 | 0.89 | ATM (0.47) | PIK3C3ATMPIK3CAPRKDCPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042900-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | Fujifilm Corporation (JP) | 2016-07-13 | — | — | EP | disclosed |