Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 7/20 | 0.45 |
| ▸ | PIK3C3 | Q8NEB9 | 4/20 | 0.45 |
| ▸ | TBK1 | Q9UHD2 | 4/20 | 0.41 |
| ▸ | PRKDC | P78527 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.34 |
| ▸ | BCL6 | P41182 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MST1 | P26927 | 1/20 | 0.33 |
| ▸ | STK4 | Q13043 | 1/20 | 0.33 |
| ▸ | STK3 | Q13188 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | STK26 | Q9P289 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17819729 | 0.90 | ATM (0.46) | ATMPIK3C3PRKDCPIK3CAAKT1 | |
| SCHEMBL17820249 | 0.90 | ATM (0.48) | ATMPIK3C3PRKDCPIK3CAPIK3CB | |
| SCHEMBL17820130 | 0.89 | ATM (0.46) | ATMPIK3C3TBK1PRKDCPIK3CA | |
| SCHEMBL17906932 | 0.88 | ATM (0.57) | ATMPIK3C3TBK1PRKDCPIK3CA | |
| SCHEMBL17906856 | 0.88 | PIK3C3 (0.46) | ATMPIK3C3PRKDCPIK3CAAKT1 | |
| SCHEMBL17819416 | 0.88 | ATM (0.47) | ATMPIK3C3TBK1PRKDCPIK3CA | |
| SCHEMBL17821092 | 0.88 | ATM (0.46) | ATMPIK3C3PRKDCPIK3CAPIK3CB | |
| SCHEMBL17820371 | 0.87 | ATM (0.48) | ATMPIK3C3PRKDCPIK3CAPIK3CB | |
| SCHEMBL17820228 | 0.87 | ATM (0.47) | ATMPIK3C3PRKDCPIK3CAPIK3CB | |
| SCHEMBL17820678 | 0.86 | ATM (0.47) | ATMPIK3C3PRKDCPIK3CAAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042900-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | Fujifilm Corporation (JP) | 2016-07-13 | — | — | EP | disclosed |