Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 9/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.53 |
| ▸ | PIK3C3 | Q8NEB9 | 6/20 | 0.52 |
| ▸ | PRKDC | P78527 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17820554 | 0.95 | ATM (0.51) | ATMPIK3CAPIK3C3PRKDCPIK3CB | |
| SCHEMBL17820405 | 0.92 | ATM (0.47) | ATMPIK3CAPIK3C3PRKDCPIK3CB | |
| SCHEMBL17820239 | 0.92 | ATM (0.50) | ATMPIK3CAPIK3C3PRKDCPIK3CB | |
| SCHEMBL17821078 | 0.92 | ATM (0.50) | ATMPIK3CAPIK3C3PRKDCPIK3CB | |
| SCHEMBL17820402 | 0.92 | ATM (0.46) | ATMPIK3CAPIK3C3PRKDCPIK3CB | |
| SCHEMBL17820250 | 0.91 | ATM (0.47) | ATMPIK3CAPIK3C3PRKDCPIK3CB | |
| SCHEMBL17820576 | 0.91 | ATM (0.51) | ATMPIK3CAPIK3C3PRKDCPIK3CB | |
| SCHEMBL17819578 | 0.90 | ATM (0.46) | ATMPIK3CAPIK3C3PRKDCPIK3CB | |
| SCHEMBL17819764 | 0.90 | ATM (0.48) | ATMPIK3CAPIK3C3PRKDCPIK3CB | |
| SCHEMBL17821114 | 0.90 | ATM (0.51) | ATMPIK3CAPIK3C3PRKDCPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042900-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | Fujifilm Corporation (JP) | 2016-07-13 | — | — | EP | disclosed |