SCHEMBL17907172

SCHEMBL17907172

O=C1CC(CC2CC(=O)NC2=O)C(=O)N1

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAP3K14 Q99558 1/20 0.48
GLA P06280 1/20 0.42
CRBN Q96SW2 12/20 0.40
DDB1 Q16531 2/20 0.37
CYP19A1 P11511 1/20 0.36
FFAR1 O14842 1/20 0.36
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
PKM P14618 1/20 0.35
NPC1 O15118 1/20 0.33
IDO1 P14902 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10573688 0.82
SCHEMBL2915829 0.80
SCHEMBL18909611 0.80
SCHEMBL5779882 0.80
SCHEMBL13378339 0.80
SCHEMBL19839455 0.80
SCHEMBL11274777 0.80 MAP3K14 (0.44) MAP3K14GLACRBNDDB1CYP19A1
SCHEMBL1818235 0.80
SCHEMBL23199745 0.78 MAP3K14 (0.43) MAP3K14GLACRBNDDB1CYP19A1
SCHEMBL1536267 0.78 MAP3K14 (0.43) MAP3K14GLACRBNDDB1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3659695-A1 HIGHLY CROSSLINKED HYBRID POLYIMIDE-SILSESQUIOXANE MEMBRANES Universiteit Twente (NL) 2020-06-03 EP disclosed
EP-3041599-B1 HIGHLY CROSSLINKED HYBRID POLYIMIDE-SILSESQUIOXANE MEMBRANES UNIV TWENTE (NL) 2019-10-30 EP disclosed
US-10052592-B2 Highly crosslinked hybrid polyimide-silsesquioxane membranes UNIVERSITEIT TWENTE (NL) 2018-08-21 US disclosed
US-20160199791-A1 HIGHLY CROSSLINKED HYBRID POLYIMIDE-SILSESQUIOXANE MEMBRANES UNIVERSITEIT TWENTE (NL) 2016-07-14 US disclosed
EP-3041599-A1 HIGHLY CROSSLINKED HYBRID POLYIMIDE-SILSESQUIOXANE MEMBRANES Universiteit Twente (NL) 2016-07-13 EP disclosed