Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17906821 | 0.91 | PIK3C3 (0.40) | PIK3C3ATMMAPTKDM4EALOX12 | |
| SCHEMBL17907109 | 0.90 | PIK3C3 (0.43) | PIK3C3ATMRAB9AMAPTKDM4E | |
| SCHEMBL17907030 | 0.90 | PIK3C3 (0.44) | PIK3C3ATMMAPTKDM4EALOX12 | |
| SCHEMBL17906849 | 0.88 | ATM (0.51) | PIK3C3ATMRAB9AMAPTKDM4E | |
| SCHEMBL17819887 | 0.87 | ATM (0.46) | PIK3C3ATMRAB9AMAPTKDM4E | |
| SCHEMBL17906781 | 0.87 | PIK3C3 (0.40) | PIK3C3ATMRAB9AMAPTKDM4E | |
| SCHEMBL17907051 | 0.86 | PIK3C3 (0.42) | PIK3C3ATMRAB9AMAPTKDM4E | |
| SCHEMBL17821069 | 0.86 | ATM (0.47) | PIK3C3ATMRAB9AMAPTKDM4E | |
| SCHEMBL17819523 | 0.86 | PIK3C3 (0.45) | PIK3C3ATMMAPTKDM4EALOX12 | |
| SCHEMBL17906982 | 0.86 | PIK3C3 (0.40) | PIK3C3ATMRAB9AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042900-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | Fujifilm Corporation (JP) | 2016-07-13 | — | — | EP | disclosed |