Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 9/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17819938 | 0.91 | ATM (0.46) | PIK3C3ATMPRKDCPIK3CBRIPK2 | |
| SCHEMBL17819611 | 0.87 | PIK3C3 (0.47) | PIK3C3ATMPRKDCPIK3CBSOS1 | |
| SCHEMBL17819786 | 0.86 | PIK3C3 (0.42) | PIK3C3ATMLRRK2PIK3CBSOS1 | |
| SCHEMBL17906661 | 0.86 | PIK3C3 (0.41) | PIK3C3ATMPRKDCPIK3CBSOS1 | |
| SCHEMBL17906603 | 0.82 | ATM (0.45) | PIK3C3ATMPRKDCPIK3CBRIPK2 | |
| SCHEMBL17828209 | 0.82 | PIK3C3 (0.49) | PIK3C3ATMPRKDCPIK3CB | |
| SCHEMBL17906729 | 0.81 | ATM (0.44) | PIK3C3ATMPRKDCPIK3CBRIPK2 | |
| SCHEMBL17907119 | 0.79 | PIK3C3 (0.40) | PIK3C3ATMPRKDCPIK3CBRIPK2 | |
| SCHEMBL17819739 | 0.79 | PIK3C3 (0.43) | PIK3C3ATMPRKDCLRRK2PIK3CB | |
| SCHEMBL17906793 | 0.79 | PIK3C3 (0.41) | PIK3C3ATMPIK3CBSOS1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042900-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | Fujifilm Corporation (JP) | 2016-07-13 | — | — | EP | disclosed |