Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 7/20 | 0.46 |
| ▸ | PIK3C3 | Q8NEB9 | 7/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.38 |
| ▸ | PRKDC | P78527 | 2/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 6/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17906757 | 0.91 | ATM (0.45) | ATMPIK3C3PIK3CAPRKDCPIK3CB | |
| SCHEMBL17820649 | 0.91 | PIK3C3 (0.48) | ATMPIK3C3PIK3CAPRKDCPIK3CB | |
| SCHEMBL17819453 | 0.90 | ATM (0.44) | ATMPIK3C3PIK3CAPRKDCPIK3CB | |
| SCHEMBL17819954 | 0.90 | ATM (0.44) | ATMPIK3C3PIK3CAPRKDCPIK3CB | |
| SCHEMBL17820226 | 0.90 | ATM (0.45) | ATMPIK3C3PIK3CAPRKDCPIK3CB | |
| SCHEMBL17821107 | 0.90 | ATM (0.44) | ATMPIK3C3PIK3CAPRKDCPIK3CB | |
| SCHEMBL17820152 | 0.86 | PIK3C3 (0.47) | ATMPIK3C3PIK3CAPRKDCPIK3CB | |
| SCHEMBL17821067 | 0.85 | PIK3C3 (0.46) | ATMPIK3C3PIK3CAPRKDCPIK3CB | |
| SCHEMBL17820318 | 0.85 | ATM (0.44) | ATMPIK3C3PIK3CAPRKDCPIK3CB | |
| SCHEMBL17820459 | 0.85 | ATM (0.46) | ATMPIK3C3PIK3CAPRKDCPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042900-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | Fujifilm Corporation (JP) | 2016-07-13 | — | — | EP | disclosed |