Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 13/20 | 0.57 |
| ▸ | PIK3C3 | Q8NEB9 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.38 |
| ▸ | PRKDC | P78527 | 3/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17820997 | 0.91 | ATM (0.48) | ATMPIK3C3RAB9APIK3CAPRKDC | |
| SCHEMBL17906932 | 0.90 | ATM (0.57) | ATMPIK3C3RAB9APIK3CAPRKDC | |
| SCHEMBL17820084 | 0.88 | ATM (0.48) | ATMPIK3C3RAB9APIK3CAPRKDC | |
| SCHEMBL17819450 | 0.87 | ATM (0.55) | ATMPIK3C3RAB9APIK3CAPRKDC | |
| SCHEMBL17906628 | 0.87 | ATM (0.52) | ATMPIK3C3RAB9APIK3CAPRKDC | |
| SCHEMBL17819494 | 0.87 | ATM (0.46) | ATMPIK3C3RAB9APIK3CACLK1 | |
| SCHEMBL17820228 | 0.86 | ATM (0.47) | ATMPIK3C3PIK3CAPRKDCPIK3CB | |
| SCHEMBL17819908 | 0.86 | ATM (0.51) | ATMPIK3C3RAB9APIK3CAPRKDC | |
| SCHEMBL17820130 | 0.85 | ATM (0.46) | ATMPIK3C3RAB9APIK3CAPRKDC | |
| SCHEMBL17820678 | 0.85 | ATM (0.47) | ATMPIK3C3PIK3CAPRKDCPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3042900-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | Fujifilm Corporation (JP) | 2016-07-13 | — | — | EP | disclosed |