SCHEMBL17907458

SCHEMBL17907458

CC1CCCN(C(=O)c2ccc3ccccc3c2C=O)C1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
HPGD P15428 6/20 0.47
RECQL P46063 1/20 0.47
GAA P10253 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
MAPT P10636 3/20 0.45
ALDH1A1 P00352 3/20 0.45
TP53 P04637 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
KDM4E B2RXH2 1/20 0.43
GLA P06280 1/20 0.43
TSHR P16473 1/20 0.43
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17907459 0.84 HPGD (0.60) HPGDRECQLGAASMN1; SMN2MAPT
SCHEMBL19119339 0.82 HPGD (0.59) HPGDGAASMN1; SMN2MAPTALDH1A1
SCHEMBL17907454 0.82 HPGD (0.59) HPGDGAASMN1; SMN2MAPTALDH1A1
SCHEMBL17907444 0.82 HPGD (0.59) HPGDGAASMN1; SMN2MAPTALDH1A1
SCHEMBL17907461 0.82 HPGD (0.59) HPGDGAASMN1; SMN2MAPTALDH1A1
SCHEMBL14720665 0.82 HPGD (0.59) HPGDGAASMN1; SMN2MAPTALDH1A1
SCHEMBL28565289 0.79 MEN1 (0.54) MEN1KMT2AHPGDRECQLGAA
SCHEMBL10720887 0.78 RECQL (0.63) MEN1KMT2AHPGDRECQLGAA
SCHEMBL28564684 0.75 MEN1 (0.49) MEN1KMT2AHPGDRECQLGAA
SCHEMBL21327876 0.75 PDE2A (0.78)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11529787-B2 Multilayer tubes UBE INDUSTRIES, LTD. (JP) 2022-12-20 US disclosed
US-11254082-B2 Multi-layer tube UBE INDUSTRIES, LTD. (JP) 2022-02-22 US disclosed
EP-3437850-B1 MULTILAYER TUBE UBE INDUSTRIES (JP) 2021-05-12 EP disclosed
US-10663092-B2 Multilayer tube UBE INDUSTRIES, LTD. (JP) 2020-05-26 US disclosed
EP-3042758-B1 LAMINATED TUBE UBE INDUSTRIES (JP) 2020-05-06 EP disclosed
EP-3461631-A1 MULTILAYER TUBE Ube Industries, Ltd. (JP) 2019-04-03 EP disclosed
US-20190091962-A1 MULTILAYER TUBES UBE INDUSTRIES, LTD. (JP) 2019-03-28 US disclosed
EP-3437850-A1 MULTILAYER TUBE UBE Industries, Ltd. (JP) 2019-02-06 EP disclosed
EP-3192650-B1 LAYERED TUBE UBE INDUSTRIES (JP) 2019-01-23 EP disclosed
US-20170261133-A1 MULTILAYER TUBE UBE INDUSTRIES, LTD. (JP) 2017-09-14 US disclosed
EP-3192650-A1 LAYERED TUBE UBE Industries, Ltd. (JP) 2017-07-19 EP disclosed
US-20160214343-A1 MULTI-LAYER TUBE UBE INDUSTRIES, LTD. (JP) 2016-07-28 US disclosed
EP-3042758-A1 LAMINATED TUBE UBE Industries, Ltd. (JP) 2016-07-13 EP disclosed