Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.56 |
| ▸ | PTGDR | Q13258 | 7/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17907940 | 0.90 | PTGDR2 (0.59) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL17907943 | 0.90 | PTGDR2 (0.59) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL17907959 | 0.90 | PTGDR2 (0.56) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL17907938 | 0.90 | PTGDR2 (0.62) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL17908003 | 0.87 | PTGDR2 (0.61) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL13279672 | 0.86 | PTGDR2 (0.58) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL17907925 | 0.86 | PTGDR2 (0.58) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL17907921 | 0.84 | PTGDR2 (0.46) | PTGDR2PTGDR | |
| SCHEMBL17907926 | 0.78 | PTGDR2 (0.47) | PTGDR2PTGDRTBXA2R | |
| SCHEMBL13281979 | 0.76 | PTGDR2 (0.54) | PTGDR2PTGDRTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697223-B1 | 7-(HETEROARYL-AMINO)-6,7,8,9-TETRAHYDROPYRIDO[1,2-A]INDOL ACETIC ACID DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS | ACTELION PHARMACEUTICALS LTD (CH) | 2016-07-13 | — | — | EP | disclosed |