Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.51 |
| ▸ | UBE2M | P61081 | 2/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17907970 | 0.91 | PTGDR2 (0.49) | PTGDR2PTGDR | |
| SCHEMBL17908000 | 0.88 | PTGDR2 (0.48) | PTGDR2PTGDR | |
| SCHEMBL17907921 | 0.87 | PTGDR2 (0.46) | PTGDR2PTGDR | |
| SCHEMBL17907962 | 0.86 | PTGDR2 (0.46) | PTGDR2PTGDR | |
| SCHEMBL17908003 | 0.85 | PTGDR2 (0.61) | PTGDR2PTGDR | |
| SCHEMBL17908004 | 0.85 | PTGDR2 (0.50) | PTGDR2PTGDR | |
| SCHEMBL17907973 | 0.85 | PTGDR2 (0.47) | PTGDR2UBE2MDCUN1D1PTGDR | |
| SCHEMBL17907931 | 0.83 | PTGDR2 (0.47) | PTGDR2PTGDR | |
| SCHEMBL17907941 | 0.81 | PTGDR2 (0.47) | PTGDR2PTGDR | |
| SCHEMBL17907940 | 0.76 | PTGDR2 (0.59) | PTGDR2PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697223-B1 | 7-(HETEROARYL-AMINO)-6,7,8,9-TETRAHYDROPYRIDO[1,2-A]INDOL ACETIC ACID DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS | ACTELION PHARMACEUTICALS LTD (CH) | 2016-07-13 | — | — | EP | disclosed |