Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 5/20 | 0.60 |
| ▸ | MAX | P61244 | 4/20 | 0.60 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17927289 | 1.00 | MYC (0.60) | MYCMAXCISD1MAPK1MAOA | |
| SCHEMBL17927320 | 0.81 | MAPK1 (0.71) | MYCMAXCISD1MAPK1MAOA | |
| SCHEMBL17927322 | 0.81 | MAPK1 (0.71) | MYCMAXCISD1MAPK1MAOA | |
| SCHEMBL17927295 | 0.78 | MYC (0.70) | MYCMAXCISD1PPARGNPC1 | |
| SCHEMBL17927296 | 0.78 | MYC (0.70) | MYCMAXCISD1PPARGNPC1 | |
| SCHEMBL17934519 | 0.76 | MYC (0.63) | MYCMAXCISD1MAOBAURKA | |
| SCHEMBL31376923 | 0.76 | MYC (0.68) | MYCMAXNPC1 | |
| SCHEMBL17927337 | 0.75 | MAPK1 (0.60) | MYCMAXCISD1MAPK1MAOA | |
| SCHEMBL17927339 | 0.75 | MAPK1 (0.60) | MYCMAXCISD1MAPK1MAOA | |
| SCHEMBL15828907 | 0.75 | CISD1 (0.72) | MYCMAXCISD1MAPK1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016115360-A1 | C-MYC LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2016-07-21 | — | — | WO | disclosed |
| WO-2016115360-A1 | C-MYC LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2016-07-21 | — | — | WO | disclosed |