Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 4/20 | 0.57 |
| ▸ | MAX | P61244 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17927363 | 1.00 | MYC (0.57) | MYCMAXALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL17934485 | 0.94 | MYC (0.55) | MYCMAXCISD1KDRMAPK1 | |
| SCHEMBL17927407 | 0.87 | MYC (0.57) | MYCMAXKDRPTPN1ACP1 | |
| SCHEMBL17927408 | 0.87 | MYC (0.57) | MYCMAXKDRPTPN1ACP1 | |
| SCHEMBL17927370 | 0.82 | MYC (0.60) | MYCMAXALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL17927372 | 0.82 | MYC (0.60) | MYCMAXALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL17927314 | 0.81 | MYC (0.52) | MYCMAXALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL17927317 | 0.81 | MYC (0.52) | MYCMAXALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL17927375 | 0.79 | MYC (0.60) | MYCMAXALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL17927373 | 0.79 | MYC (0.60) | MYCMAXALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016115360-A1 | C-MYC LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2016-07-21 | — | — | WO | claimed |