Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 15/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.70 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.70 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.70 |
| ▸ | CTSK | P43235 | 4/20 | 0.67 |
| ▸ | CHKA | P35790 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CTSH | P09668 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17924021 | 1.00 | CTSC (0.71) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL17924020 | 1.00 | CTSC (0.71) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL12687941 | 0.91 | CTSC (0.67) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL12494849 | 0.91 | CTSC (0.58) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL12494857 | 0.91 | CTSC (0.58) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL12494797 | 0.90 | CTSC (0.69) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL12494863 | 0.90 | CTSC (0.69) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL12687903 | 0.90 | CTSC (0.57) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL19869129 | 0.90 | CTSC (0.58) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL12687902 | 0.89 | CTSC (0.57) | CTSCKCNH2LTB4RLTB4R2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9856228-B2 | Peptidyl nitril compounds as dipeptidyl peptidase I inhibitors | PROZYMEX A/S (DK) | 2018-01-02 | — | — | US | disclosed |
| US-20160207900-A1 | PEPTIDYL NITRIL COMPOUNDS AS DIPEPTIDYL PEPTIDASE I INHIBITORS | PROZYMEX A/S (DK) | 2016-07-21 | — | — | US | disclosed |
| US-20160207900-A1 | PEPTIDYL NITRIL COMPOUNDS AS DIPEPTIDYL PEPTIDASE I INHIBITORS | PROZYMEX A/S (DK) | 2016-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160207900-A1 | PEPTIDYL NITRIL COMPOUNDS AS DIPEPTIDYL PEPTIDASE I INHIBITORS | DPP4, DPP3, DPP8 | CTSC 7/4885KCNH2 3882/4885LTB4R 2375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.