Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 1/20 | 0.34 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.34 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.31 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.31 |
| ▸ | POLA1 | P09884 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10238944 | 1.00 | P2RY2 (0.34) | P2RY2P2RY4SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL10238924 | 1.00 | P2RY2 (0.34) | P2RY2P2RY4SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL10238930 | 1.00 | P2RY2 (0.34) | P2RY2P2RY4SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL9101921 | 1.00 | P2RY2 (0.34) | P2RY2P2RY4SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL4292909 | 1.00 | P2RY2 (0.34) | P2RY2P2RY4SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL10238939 | 0.88 | P2RY2 (0.35) | P2RY2P2RY4SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL10238955 | 0.88 | P2RY2 (0.35) | P2RY2P2RY4SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL10238932 | 0.86 | P2RY2 (0.34) | P2RY2P2RY4SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL10238951 | 0.86 | P2RY2 (0.34) | P2RY2P2RY4SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL17357584 | 0.86 | P2RY2 (0.41) | P2RY2P2RY4SLC28A1SLC28A2SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9394331-B2 | 2′-spiro-nucleosides and derivatives thereof useful for treating hepatitis C virus and dengue virus infections | GILEAD PHARMASSET LLC (US) | 2016-07-19 | — | — | US | disclosed |