Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA7 | P43166 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17933974 | 0.98 | CA12 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL21712104 | 0.87 | EPHX2 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL26146672 | 0.85 | EPHX2 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30057722 | 0.85 | EPHX2 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL21609804 | 0.84 | EPHX2 (0.60) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1427364 | 0.82 | CA12 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30057714 | 0.82 | EPHX2 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL26146670 | 0.82 | EPHX2 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2562838 | 0.81 | EPHX2 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL21712026 | 0.80 | EPHX2 (0.46) | EPHX2PDE5AHSD17B10KMT2APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016112863-A1 | N-SUBSTITUTED-3,5-DISUBSTITUTED BENZAMIDE COMPOUND AND PREPARATION METHOD AND APPLICATION THEREOF | 中国科学院上海药物研究所 | 2016-07-21 | — | — | WO | disclosed |