Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 15/20 | 0.71 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MAX | P61244 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17934016 | 0.90 | MYC (0.75) | MYCMEN1KMT2AMAXPOLB | |
| SCHEMBL17934468 | 0.89 | MYC (0.76) | MYCMEN1KMT2AMAXPOLB | |
| SCHEMBL17934017 | 0.86 | MYC (0.72) | MYCMEN1KMT2AMAXPOLB | |
| SCHEMBL26266093 | 0.86 | MYC (0.75) | MYCMEN1KMT2AMAXPOLB | |
| SCHEMBL17927384 | 0.84 | MYC (0.82) | MYCMEN1KMT2AMAXPOLB | |
| SCHEMBL17927359 | 0.83 | MYC (1.00) | MYCMEN1KMT2AMAXPOLB | |
| SCHEMBL17927410 | 0.82 | MYC (0.73) | MYCMEN1KMT2AMAXPOLB | |
| SCHEMBL17934013 | 0.78 | MYC (0.52) | MYCMEN1KMT2APOLBL3MBTL1 | |
| SCHEMBL17934532 | 0.76 | MYC (0.68) | MYCMEN1KMT2AMAXPOLB | |
| SCHEMBL17927299 | 0.75 | MYC (0.70) | MYCMEN1KMT2AMAXPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016115360-A1 | C-MYC LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2016-07-21 | — | — | WO | disclosed |