Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 7/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | MAX | P61244 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 3/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17934594 | 0.86 | MYC (0.71) | MYCHTTPOLBMEN1KMT2A | |
| SCHEMBL6986059 | 0.76 | HTT (1.00) | HTTPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17927410 | 0.76 | MYC (0.73) | MYCHTTPOLBMEN1KMT2A | |
| SCHEMBL17927384 | 0.76 | MYC (0.82) | MYCHTTPOLBMEN1KMT2A | |
| SCHEMBL17927359 | 0.76 | MYC (1.00) | MYCHTTPOLBMEN1KMT2A | |
| SCHEMBL17934577 | 0.76 | MYC (0.63) | MYCHTTPOLBMEN1KMT2A | |
| SCHEMBL17927368 | 0.73 | MYC (0.72) | MYCHTTPOLBMEN1KMT2A | |
| SCHEMBL17927364 | 0.73 | MYC (0.72) | MYCHTTPOLBMEN1KMT2A | |
| SCHEMBL17927401 | 0.73 | MYC (0.69) | MYCHTTPOLBMEN1KMT2A | |
| SCHEMBL17934468 | 0.73 | MYC (0.76) | MYCHTTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016115360-A1 | C-MYC LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2016-07-21 | — | — | WO | disclosed |