Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 2/20 | 0.75 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.60 |
| ▸ | NPC1L1 | Q9UHC9 | 4/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | OSBP | P22059 | 1/20 | 0.56 |
| ▸ | RORC | P51449 | 1/20 | 0.56 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.56 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.55 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.55 |
| ▸ | GBA1 | P04062 | 2/20 | 0.55 |
| ▸ | UGCG | Q16739 | 2/20 | 0.55 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | FNTA | P49354 | 1/20 | 0.51 |
| ▸ | FNTB | P49356 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22919706 | 0.90 | POLA1 (0.68) | POLA1CYP46A1NPC1L1USP2LMNA | |
| SCHEMBL22919698 | 0.90 | POLA1 (0.68) | POLA1CYP46A1NPC1L1USP2LMNA | |
| SCHEMBL22919661 | 0.90 | POLA1 (0.68) | POLA1CYP46A1NPC1L1USP2LMNA | |
| SCHEMBL23453005 | 0.90 | POLA1 (0.68) | POLA1CYP46A1NPC1L1USP2LMNA | |
| SCHEMBL26716785 | 0.90 | POLA1 (0.68) | POLA1CYP46A1NPC1L1USP2LMNA | |
| SCHEMBL23452794 | 0.90 | POLA1 (0.68) | POLA1CYP46A1NPC1L1USP2LMNA | |
| SCHEMBL23451185 | 0.90 | POLA1 (0.68) | POLA1CYP46A1NPC1L1USP2LMNA | |
| SCHEMBL23451223 | 0.90 | POLA1 (0.68) | POLA1CYP46A1NPC1L1USP2LMNA | |
| SCHEMBL23451218 | 0.90 | POLA1 (0.68) | POLA1CYP46A1NPC1L1USP2LMNA | |
| SCHEMBL23451215 | 0.90 | POLA1 (0.68) | POLA1CYP46A1NPC1L1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9393200-B2 | Lipopolyamines of spermine type for construction of liposomal transfection systems | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) | 2016-07-19 | — | — | US | disclosed |