Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 11/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | LDHB | P07195 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17945938 | 0.91 | CASR (0.54) | CASRPPARG | |
| SCHEMBL17939825 | 0.91 | CASR (0.54) | CASRPPARG | |
| SCHEMBL16540311 | 0.91 | CASR (0.42) | CASRLDHALDHBPPARG | |
| SCHEMBL17945546 | 0.91 | CASR (0.42) | CASRLDHALDHBPPARG | |
| Hydrochloric Acid SCHEMBL17939871 | 0.91 | CASR (0.53) | CASRPPARG | |
| Hydrochloric Acid SCHEMBL17939869 | 0.91 | CASR (0.53) | CASRPPARG | |
| Hydrochloric Acid SCHEMBL17939890 | 0.90 | CASR (0.41) | CASRLDHALDHBPPARG | |
| Hydrochloric Acid SCHEMBL17939888 | 0.90 | CASR (0.41) | CASRLDHALDHBPPARG | |
| SCHEMBL16540583 | 0.90 | CASR (0.44) | CASRLDHALDHBPPARG | |
| SCHEMBL16548315 | 0.90 | CASR (0.44) | CASRLDHALDHBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160214924-A1 | SUBSTITUTED NAPHTHALENE COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS | LUPIN ATLANTIS HOLDINGS SA (CH) | 2016-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160214924-A1 | SUBSTITUTED NAPHTHALENE COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS | CASR, RYR2, RYR1 | CASR 1/4885LDHA 4188/4885LDHB 4467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.