Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16618261 | 0.91 | SCN9A (1.00) | SCN9ASCN5A | |
| SCHEMBL17940185 | 0.90 | SCN9A (1.00) | SCN9ASCN5A | |
| SCHEMBL16618370 | 0.88 | SCN9A (1.00) | SCN9ASCN5A | |
| SCHEMBL17940405 | 0.86 | SCN9A (1.00) | SCN9ASCN5A | |
| SCHEMBL17940240 | 0.86 | SCN9A (1.00) | SCN9ASCN5A | |
| SCHEMBL16618388 | 0.84 | SCN9A (1.00) | SCN9ASCN5A | |
| SCHEMBL17940402 | 0.84 | SCN9A (1.00) | SCN9ASCN5A | |
| SCHEMBL17940210 | 0.84 | SCN9A (1.00) | SCN9ASCN5A | |
| SCHEMBL17940258 | 0.83 | SCN9A (1.00) | SCN9ASCN5A | |
| SCHEMBL16618256 | 0.83 | SCN9A (1.00) | SCN9ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663508-B2 | Biaryl acyl-sulfonamide compounds as sodium channel inhibitors | AMGEN INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-20160214971-A1 | Biaryl Acyl-Sulfonamide Compounds as Sodium Channel Inhibitors | One Amgen Center Drive (US) | 2016-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160214971-A1 | Biaryl Acyl-Sulfonamide Compounds as Sodium Channel Inhibitors | SCN1A, SCN1B, SCN5A | SCN9A 9/4885SCN5A 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.