SCHEMBL17944348

SCHEMBL17944348

c1ccc(-c2ccc3cc(-c4c5ccccc5c(-c5cccc6c5sc5c7ccccc7ccc65)c5ccccc45)ccc3c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 5/20 0.47
CYP1B1 Q16678 5/20 0.47
CYP1A2 P05177 5/20 0.40
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
SOS1 Q07889 1/20 0.36
ESR1 P03372 4/20 0.36
ESR2 Q92731 4/20 0.36
HSD17B1 P14061 4/20 0.36
HSD17B2 P37059 4/20 0.36
F9 P00740 2/20 0.35
CYP3A4 P08684 2/20 0.35
CYP2D6 P10635 2/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2B6 P20813 2/20 0.35
CYP2C19 P33261 2/20 0.35
ALOX5 P09917 1/20 0.35
LIMK1 P53667 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17945304 0.95 CYP1A1 (0.44) CYP1A1CYP1B1CYP1A2CA12CA1
SCHEMBL22707478 0.93 CYP1A1 (0.42) CYP1A1CYP1B1CYP1A2CA12CA1
SCHEMBL17944684 0.93 CYP1A1 (0.43) CYP1A1CYP1B1CYP1A2SOS1HSD17B1
SCHEMBL17945223 0.92 CYP1A1 (0.48) CYP1A1CYP1B1CYP1A2CA12CA1
SCHEMBL26003233 0.92 CYP1A1 (0.40) CYP1A1CYP1B1CYP1A2CA12CA1
SCHEMBL17944390 0.91 CYP1A1 (0.48) CYP1A1CYP1B1CYP1A2ESR1ESR2
SCHEMBL19080355 0.89 CYP1A1 (0.43) CYP1A1CYP1B1CYP1A2CA12CA1
SCHEMBL17943949 0.89 CYP1A1 (0.50) CYP1A1CYP1B1CYP1A2SOS1ESR1
SCHEMBL17944445 0.88 CYP1A1 (0.42) CYP1A1CYP1B1CYP1A2CA12CA1
SCHEMBL17944384 0.88 CYP1A1 (0.45) CYP1A1CYP1B1CYP1A2HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160218297-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-28 US disclosed
US-20160218297-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-28 US disclosed