Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | BCL2 | P10415 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | SOD1 | P00441 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17954206 | 0.89 | F2 (0.51) | TSHRSMN1; SMN2NR4A2CYP4F2CYP4A11 | |
| SCHEMBL17954222 | 0.87 | FFAR1 (0.52) | SMN1; SMN2NR4A2BCL2MRGPRX4F2 | |
| SCHEMBL13462828 | 0.87 | MAOB (0.58) | NR4A2CYP4F2CYP4A11SMPD1MRGPRX4 | |
| SCHEMBL3683352 | 0.82 | MRGPRX4 (0.61) | TSHRSMN1; SMN2NR4A2CYP4F2CYP4A11 | |
| SCHEMBL17954221 | 0.82 | CYP4F2 (0.51) | TSHRSMN1; SMN2NR4A2CYP4F2CYP4A11 | |
| SCHEMBL12894971 | 0.82 | BCL2 (0.62) | TSHRBCL2PRKCIPTGS2FYN | |
| SCHEMBL13766439 | 0.82 | PRKCI (0.59) | BCL2PRKCIPTGS2FYN | |
| SCHEMBL17954211 | 0.81 | FFAR1 (0.48) | TSHRSMN1; SMN2CYP4F2CYP4A11MRGPRX4 | |
| SCHEMBL17954216 | 0.81 | MRGPRX4 (0.50) | TSHRSMN1; SMN2NR4A2CYP4F2CYP4A11 | |
| SCHEMBL18102828 | 0.81 | MRGPRX4 (0.62) | NR4A2BCL2MRGPRX4F2SOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160215288-A1 | ORGANIC COMPOUNDS TO TREAT HEPATITIS B VIRUS | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC. | 2016-07-28 | — | — | US | disclosed |