Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 20/20 | 0.69 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17519909 | 0.91 | AR (0.71) | ARCRBN | |
| SCHEMBL25315777 | 0.90 | AR (0.72) | ARCRBN | |
| SCHEMBL22565314 | 0.90 | AR (0.72) | ARCRBN | |
| SCHEMBL17941338 | 0.89 | AR (0.68) | ARCRBN | |
| SCHEMBL17941339 | 0.89 | AR (0.68) | ARCRBN | |
| SCHEMBL22197929 | 0.89 | AR (0.73) | ARCRBN | |
| SCHEMBL31061198 | 0.89 | AR (0.73) | ARCRBN | |
| SCHEMBL17941080 | 0.89 | AR (0.73) | ARCRBN | |
| SCHEMBL17523083 | 0.89 | AR (0.73) | ARCRBN | |
| SCHEMBL17519966 | 0.89 | AR (0.73) | ARCRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016118666-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF THE ANDROGEN RECEPTOR | Arvinas, Inc. (US) | 2016-07-28 | — | — | WO | disclosed |