SCHEMBL17954875

SCHEMBL17954875

c1ccc(-c2nnc(-c3ccccc3N3c4ccccc4N(c4ccccc4)c4ccccc43)n2-c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 3/20 0.50
AVPR1A P37288 1/20 0.49
ALDH1A1 P00352 4/20 0.48
KDM4E B2RXH2 3/20 0.48
HSD17B10 Q99714 3/20 0.48
TSHR P16473 1/20 0.48
HPGD P15428 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
GLA P06280 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
CES2 O00748 1/20 0.40
BCHE P06276 1/20 0.40
GAA P10253 1/20 0.40
CES1 P23141 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17951539 0.89 AVPR1A (0.56) AKT1AVPR1AALDH1A1KDM4EHSD17B10
SCHEMBL17536166 0.87 AVPR1A (0.59) AVPR1AALDH1A1KDM4EHSD17B10TSHR
SCHEMBL29362431 0.87 AVPR1A (0.59) AVPR1AALDH1A1KDM4EHSD17B10TSHR
SCHEMBL17879369 0.85 AVPR1A (0.56) AVPR1AALDH1A1KDM4EHSD17B10TSHR
SCHEMBL20998058 0.82 AKT1 (0.43) AKT1AVPR1AALDH1A1KDM4EHSD17B10
SCHEMBL17023639 0.81 AVPR1A (0.59) AKT1AVPR1AALDH1A1KDM4EHSD17B10
SCHEMBL17069885 0.81 AVPR1A (0.59) AKT1AVPR1AALDH1A1KDM4EHSD17B10
SCHEMBL39449 0.79 AVPR1A (0.70) AVPR1AALDH1A1KDM4EHSD17B10TSHR
SCHEMBL18327898 0.79 AVPR1A (0.70) AVPR1AALDH1A1KDM4EHSD17B10TSHR
SCHEMBL30377243 0.79 AVPR1A (0.50) AVPR1AALDH1A1KDM4EHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016116504-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC COMPONENTS CYNORA GMBH (DE) 2016-07-28 WO disclosed