Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 8/20 | 0.57 |
| ▸ | TNKS2 | Q9H2K2 | 8/20 | 0.57 |
| ▸ | SULT2A1 | Q06520 | 1/20 | 0.47 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.30 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9905220 | 0.81 | TNKS (0.62) | TNKSTNKS2SULT2A1CTSAAPLNR | |
| SCHEMBL9905223 | 0.81 | TNKS (0.62) | TNKSTNKS2SULT2A1CTSAAPLNR | |
| SCHEMBL15449830 | 0.77 | TNKS2 (0.76) | TNKSTNKS2SULT2A1APLNR | |
| SCHEMBL17955703 | 0.75 | TNKS (0.42) | TNKSTNKS2SULT2A1 | |
| SCHEMBL9905439 | 0.73 | TNKS (1.00) | TNKSTNKS2SULT2A1APLNR | |
| SCHEMBL9905440 | 0.73 | TNKS (1.00) | TNKSTNKS2SULT2A1APLNR | |
| SCHEMBL15449823 | 0.71 | TNKS (0.83) | TNKSTNKS2SULT2A1APLNR | |
| SCHEMBL9905264 | 0.70 | TNKS (0.49) | TNKSTNKS2SULT2A1 | |
| SCHEMBL9905260 | 0.70 | TNKS (0.49) | TNKSTNKS2SULT2A1 | |
| SCHEMBL9902075 | 0.70 | TNKS (0.61) | TNKSTNKS2SULT2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9403812-B2 | Triazole derivatives as Wnt signaling pathway inhibitors | OSLO UNIVERSITY HOSPITAL HF (NO) | 2016-08-02 | — | — | US | disclosed |