Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910627 | 0.93 | CHRM1 (0.34) | CHRM1GRM7NLRP3PDE4DCLK1 | |
| SCHEMBL2463456 | 0.91 | CHRM1 (0.33) | CHRM1GRM7NLRP3PDE4DCLK1 | |
| SCHEMBL2460971 | 0.89 | CHRM1 (0.36) | CHRM1GRM7NLRP3PDE4DCLK1 | |
| SCHEMBL2549541 | 0.88 | CHRM1 (0.36) | CHRM1GRM7NLRP3PDE4DCLK1 | |
| SCHEMBL2549544 | 0.88 | CHRM1 (0.36) | CHRM1GRM7NLRP3PDE4DCLK1 | |
| SCHEMBL2548972 | 0.88 | CHRM1 (0.36) | CHRM1GRM7NLRP3PDE4DCLK1 | |
| SCHEMBL2462784 | 0.87 | CHRM1 (0.34) | CHRM1GRM7NLRP3PDE4DCLK1 | |
| SCHEMBL2461073 | 0.86 | SMN1; SMN2 (0.39) | CHRM1NLRP3PDE4DCLK1RAB9A | |
| SCHEMBL2460970 | 0.85 | CHRM1 (0.38) | CHRM1GRM7NLRP3PDE4DCLK1 | |
| SCHEMBL15472261 | 0.85 | CHRM1 (0.41) | CHRM1PDE4DCLK1RAB9ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364298-B1 | QUINOLONE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMA CO LTD (JP) | 2016-08-03 | — | — | EP | disclosed |